A safe and convenient pseudovirus-based inhibition assay to detect neutralizing antibodies and screen for viral entry inhibitors against the novel human coronavirus MERS-CoV

BACKGROUND: Evidence points to the emergence of a novel human coronavirus, Middle East respiratory syndrome coronavirus (MERS-CoV), which causes a severe acute respiratory syndrome (SARS)-like disease. In response, the development of effective vaccines and therapeutics remains a clinical priority. T...

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Main Authors: Zhao, Guangyu, Du, Lanying, Ma, Cuiqing, Li, Ye, Li, Lin, Poon, Vincent KM, Wang, Lili, Yu, Fei, Zheng, Bo-Jian, Jiang, Shibo, Zhou, Yusen
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Methodology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3765664/
https://ncbi.nlm.nih.gov/pubmed/23978242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-10-266
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