The ZIP5 Ectodomain Co-Localizes with PrP and May Acquire a PrP-Like Fold That Assembles into a Dimer

The cellular prion protein (PrP(C)) was recently observed to co-purify with members of the LIV-1 subfamily of ZIP zinc transporters (LZTs), precipitating the surprising discovery that the prion gene family descended from an ancestral LZT gene. Here, we compared the subcellular distribution and bioph...

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Autori principali: Pocanschi, Cosmin L., Ehsani, Sepehr, Mehrabian, Mohadeseh, Wille, Holger, Reginold, William, Trimble, William S., Wang, Hansen, Yee, Adelinda, Arrowsmith, Cheryl H., Bozóky, Zoltán, Kay, Lewis E., Forman-Kay, Julie D., Rini, James M., Schmitt-Ulms, Gerold
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2013
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3765157/
https://ncbi.nlm.nih.gov/pubmed/24039764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0072446
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