An emerging role of the cellular prion protein as a modulator of a morphogenetic program underlying epithelial-to-mesenchymal transition

Knowledge of phenotypic changes the cellular prion protein (PrPC) contributes to may provide novel avenues for understanding its function. Here we consider data from functional knockout/down studies and protein-protein interaction analyses from the perspective of PrP’s relationship to its ancestral...

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Autori principali: Mohadeseh eMehrabian, Sepehr eEhsani, Gerold eSchmitt-Ulms
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2014-09-01
Serie:Frontiers in Cell and Developmental Biology
Soggetti:
prion protein
phenotype
function
epithelial-to-mesenchymal transition
ZIP transporter
Accesso online:http://journal.frontiersin.org/Journal/10.3389/fcell.2014.00053/full
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