Mutagenicity and tumorigenicity of the four enantiopure bay-region 3,4-diol-1,2-epoxide isomers of dibenz[a,h]anthracene

Each enantiomer of the diastereomeric pair of bay-region dibenz[a,h]anthracene 3,4-diol-1,2-epoxides in which the benzylic 4-hydroxyl group and epoxide oxygen are either cis (isomer 1) or trans (isomer 2) were evaluated for mutagenic activity. In strains TA 98 and TA 100 of Salmonella typhimurium, t...

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Hauptverfasser: Chang, Richard L., Wood, Alexander W., Huang, Mou Tuan, Xie, Jian Guo, Cui, Xiao Xing, Reuhl, Kenneth R., Boyd, D.R., Lin, Yong, Shih, Weichung Joe, Balani, Suresh K., Yagi, Haruhiko, Jerina, Donald M., Conney, Allan H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2013
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3765047/
https://ncbi.nlm.nih.gov/pubmed/23671133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgt164
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