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Caffeic acid phenethyl ester suppresses melanoma tumor growth by inhibiting PI3K/AKT/XIAP pathway

Melanoma is highly metastatic and resistant to chemotherapeutic drugs. Our previous studies have demonstrated that caffeic acid phenethyl ester (CAPE) suppresses the growth of melanoma cells and induces reactive oxygen species generation. However, the exact mechanism of the growth suppressive effect...

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Autores principales: Pramanik, Kartick C., Kudugunti, Shashi K., Fofaria, Neel M., Moridani, Majid Y., Srivastava, Sanjay K.
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3765043/
https://ncbi.nlm.nih.gov/pubmed/23640046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgt154
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