Biochemical mechanism of Caffeic Acid Phenylethyl Ester (CAPE) selective toxicity towards melanoma cell lines

In the current work, we investigated the in-vitro biochemical mechanism of caffeic acid phenylethyl ester (CAPE) toxicity and eight hydroxycinnamic/caffeic acid derivatives in-vitro, using tyrosinase enzyme as a molecular target in human SK-MEL-28 melanoma cells. Enzymatic reaction models using tyro...

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Autores principales: Kudugunti, Shashi K., Vad, Nikhil M., Whiteside, Amanda J., Naik, Bhakti U., Yusuf, Mohd. A., Srivenugopal, Kalkunte S., Moridani, Majid Y.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2932756/
https://ncbi.nlm.nih.gov/pubmed/20685355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbi.2010.05.018
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