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Pancreatic tumor suppression by benzyl isothiocyanate is associated with inhibition of PI3K/AKT/FOXO pathway
PURPOSE: Our previous studies have shown that benzyl isothiocyante (BITC) suppresses pancreatic cancer growth by inducing apoptosis but the molecular mechanism was unclear. In the present study we hypothesized the involvement of PI3K/AKT/FOXO pathway in BITC induced apoptosis. EXPERIMENTAL DESIGN: M...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3076680/ https://ncbi.nlm.nih.gov/pubmed/21350002 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-10-1891 |
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