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Deguelin Suppresses Pancreatic Tumor Growth and Metastasis by Inhibiting Epithelial to Mesenchymal Transition in an Orthotopic Model()

Deguelin is known to suppress the growth of cancer cells; however, its anti-metastatic effects have not been studied so far in any cancer model. In the present study, we aimed to evaluate the anti-metastatic potential of deguelin in vivo and in TGFβ1-stimulated cells. Our results demonstrate that tu...

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Detalhes bibliográficos
Main Authors: Boreddy, Srinivas Reddy, Srivastava, Sanjay K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3530646/
https://ncbi.nlm.nih.gov/pubmed/22986522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2012.413
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