Detailed analysis of biased histamine H(4) receptor signalling by JNJ 7777120 analogues

BACKGROUND AND PURPOSE: The histamine H(4) receptor, originally thought to signal merely through Gα(i) proteins, has recently been shown to also recruit and signal via β-arrestin2. Following the discovery that the reference antagonist indolecarboxamide JNJ 7777120 appears to be a partial agonist in...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Hoofdauteurs: Nijmeijer, S, Vischer, H F, Sirci, F, Schultes, S, Engelhardt, H, de Graaf, C, Rosethorne, E M, Charlton, S J, Leurs, R
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Blackwell Publishing Ltd 2013
Onderwerpen:
Themed Issue: Histamine Pharmacology Update
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3764851/
https://ncbi.nlm.nih.gov/pubmed/23351115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12117
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items