A Selective Histamine H(4) Receptor Antagonist, JNJ7777120, Is Protective in a Rat Model of Transient Cerebral Ischemia

Cerebral ischemia is a multifactorial pathology characterized by different events evolving in time. The acute injury, characterized by excitoxicity, is followed by a secondary brain injury that develops from hours to days after ischemia. Extracellular levels of histamine increase in the ischemic are...

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Bibliografiske detaljer
Udgivet i:Front Pharmacol
Main Authors: Dettori, Ilaria, Gaviano, Lisa, Melani, Alessia, Lucarini, Laura, Durante, Mariaconcetta, Masini, Emanuela, Pedata, Felicita
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2018
Fag:
Pharmacology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6215858/
https://ncbi.nlm.nih.gov/pubmed/30420807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.01231
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