Effects of PARP-1 Deficiency and Histamine H(4) Receptor Inhibition in an Inflammatory Model of Lung Fibrosis in Mice

Pulmonary fibrosis is the most frequent form of interstitial lung disease. Effective therapies are not yet available; novel therapeutic approaches are needed for counteracting fibrosis. Poly(ADP-ribose) polymerases are enzymes, involved in DNA repair and cell apoptosis. PARP-1 deficient mice exhibit...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Durante, Mariaconcetta, Sgambellone, Silvia, Lanzi, Cecilia, Nardini, Patrizia, Pini, Alessandro, Moroni, Flavio, Masini, Emanuela, Lucarini, Laura
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6535496/
https://ncbi.nlm.nih.gov/pubmed/31164820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00525
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