Effects of PARP-1 Deficiency and Histamine H(4) Receptor Inhibition in an Inflammatory Model of Lung Fibrosis in Mice

Pulmonary fibrosis is the most frequent form of interstitial lung disease. Effective therapies are not yet available; novel therapeutic approaches are needed for counteracting fibrosis. Poly(ADP-ribose) polymerases are enzymes, involved in DNA repair and cell apoptosis. PARP-1 deficient mice exhibit...

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Bibliografski detalji
Izdano u:Front Pharmacol
Glavni autori: Durante, Mariaconcetta, Sgambellone, Silvia, Lanzi, Cecilia, Nardini, Patrizia, Pini, Alessandro, Moroni, Flavio, Masini, Emanuela, Lucarini, Laura
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2019
Teme:
Pharmacology
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6535496/
https://ncbi.nlm.nih.gov/pubmed/31164820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00525
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