Effects of PARP-1 Deficiency and Histamine H(4) Receptor Inhibition in an Inflammatory Model of Lung Fibrosis in Mice

Pulmonary fibrosis is the most frequent form of interstitial lung disease. Effective therapies are not yet available; novel therapeutic approaches are needed for counteracting fibrosis. Poly(ADP-ribose) polymerases are enzymes, involved in DNA repair and cell apoptosis. PARP-1 deficient mice exhibit...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Front Pharmacol
Hlavní autoři: Durante, Mariaconcetta, Sgambellone, Silvia, Lanzi, Cecilia, Nardini, Patrizia, Pini, Alessandro, Moroni, Flavio, Masini, Emanuela, Lucarini, Laura
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2019
Témata:
Pharmacology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6535496/
https://ncbi.nlm.nih.gov/pubmed/31164820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00525
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky