Effects of PARP-1 Deficiency and Histamine H(4) Receptor Inhibition in an Inflammatory Model of Lung Fibrosis in Mice

Pulmonary fibrosis is the most frequent form of interstitial lung disease. Effective therapies are not yet available; novel therapeutic approaches are needed for counteracting fibrosis. Poly(ADP-ribose) polymerases are enzymes, involved in DNA repair and cell apoptosis. PARP-1 deficient mice exhibit...

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發表在:Front Pharmacol
Main Authors: Durante, Mariaconcetta, Sgambellone, Silvia, Lanzi, Cecilia, Nardini, Patrizia, Pini, Alessandro, Moroni, Flavio, Masini, Emanuela, Lucarini, Laura
格式: Artigo
語言:Inglês
出版: Frontiers Media S.A. 2019
主題:
Pharmacology
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6535496/
https://ncbi.nlm.nih.gov/pubmed/31164820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00525
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