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The Amyloid Precursor Protein Represses Expression of Acetylcholinesterase in Neuronal Cell Lines
The toxic role of amyloid β peptides in Alzheimer's disease is well documented. Their generation is via sequential β- and γ-secretase cleavage of the membrane-bound amyloid precursor protein (APP). Other APP metabolites include the soluble ectodomains sAPPα and sAPPβ and also the amyloid precur...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Biochemistry and Molecular Biology
2013
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3764808/ https://ncbi.nlm.nih.gov/pubmed/23897820 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.461269 |
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