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The E1 copper binding domain of full-length amyloid precursor protein mitigates copper-induced growth inhibition in brain metastatic prostate cancer DU145 cells

Copper plays an important role in the aetiology and growth of tumours and levels of the metal are increased in the serum and tumour tissue of patients affected by a range of cancers including prostate cancer (PCa). The molecular mechanisms that enable cancer cells to proliferate in the presence of e...

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Bibliografische gegevens
Gepubliceerd in:Biochem Biophys Res Commun
Hoofdauteurs: Gough, Mallory, Blanthorn-Hazell, Sophee, Delury, Craig, Parkin, Edward
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Academic Press 2014
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4256156/
https://ncbi.nlm.nih.gov/pubmed/25305487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2014.10.004
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