Osteoprotegerin Contributes to the Metastatic Potential of Cells with a Dysfunctional TSC2 Tumor-Suppressor Gene

In addition to its effects on bone metabolism, osteoprotegerin (OPG), a soluble member of the tumor necrosis factor family of receptors, promotes smooth muscle cell proliferation and migration and may act as a survival factor for tumor cells. We hypothesized that these cellular mechanisms of OPG may...

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Bibliographic Details
Main Authors: Steagall, Wendy K., Pacheco-Rodriguez, Gustavo, Glasgow, Connie G., Ikeda, Yoshihiko, Lin, Jing-Ping, Zheng, Gang, Moss, Joel
Format: Artigo
Language:Inglês
Published: American Society for Investigative Pathology 2013
Subjects:
Regular Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3763770/
https://ncbi.nlm.nih.gov/pubmed/23867796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2013.05.024
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