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Modulation of SAP dependent T:B cell interactions as a strategy to improve vaccination

Generating long-term humoral immunity is a crucial component of successful vaccines and requires interactions between T cells and B cells in germinal centers (GC). In GCs, a specialized subset of CD4(+) helper T cells, called T follicular helper cells (Tfh), provide help to B cells; this help direct...

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Autors principals: Hu, Joyce, Havenar-Daughton, Colin, Crotty, Shane
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3763741/
https://ncbi.nlm.nih.gov/pubmed/23743125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coviro.2013.05.015
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