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SAP modulates B cell functions in a genetic background-dependent manner

Mutations affecting the SLAM-associated protein (SAP) are responsible for the X-linked lympho-proliferative syndrome (XLP), a severe primary immunodeficiency syndrome with disease manifestations that include fatal mononucleosis, B cell lymphoma and dysgammaglobulinemia. It is well accepted that insu...

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Autori principali: Detre, Cynthia, Yigit, Burcu, Keszei, Marton, Castro, Wilson, Magelky, Erica M., Terhorst, Cox
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3758805/
https://ncbi.nlm.nih.gov/pubmed/23806511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.imlet.2013.06.003
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