Expansion of an osteopontin-expressing T follicular helper cell subset correlates with autoimmunity in B6.Sle1b mice and is suppressed by the H1-isoform of the Slamf6 receptor

The costimulatory receptor Slamf6 partially controls lupus-related autoimmunity in congenic Sle1b mice; for instance, the presence of the protein isoform Slamf6-H1 in Sle1b.Slamf6-H1 mice mitigates disease. Here, we report that young Sle1b mice, but not Sle1b.Slamf6-H1 or B6 mice, contain a memory T...

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Bibliografiset tiedot
Päätekijät: Keszei, Marton, Detre, Cynthia, Castro, Wilson, Magelky, Erica, O'Keeffe, Michael, Kis-Toth, Katalin, Tsokos, George C., Wang, Ninghai, Terhorst, Cox
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Federation of American Societies for Experimental Biology 2013
Aiheet:
Research Communications
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3714581/
https://ncbi.nlm.nih.gov/pubmed/23629864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.12-226951
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