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SLAMF6-driven co-stimulation of human peripheral T cells is defective in SLE T cells

The CD28 co-stimulatory pathway is well established for T cell activation. However, there is evidence suggesting the existence of additional co-stimulatory pathways. Here we report that a member of the SLAM superfamily, SLAMF6, or CD352 plays an important role in T cell co-stimulation. Cross-linking...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Autoimmunity
Hauptverfasser: Chatterjee, Madhumouli, Kis-Toth, Katalin, Thai, To-Ha, Terhorst, Cox, Tsokos, George C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4465387/
https://ncbi.nlm.nih.gov/pubmed/21231893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/08916934.2010.530627
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