SAP expression in invariant NKT cells is required for cognate help to support B-cell responses

One of the manifestations of X-linked lymphoproliferative disease (XLP) is progressive agammaglobulinemia, caused by the absence of a functional signaling lymphocyte activation molecule (SLAM)–associated protein (SAP) in T, invariant natural killer T (NKT) cells and NK cells. Here we report that α-g...

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Detalhes bibliográficos
Main Authors: Detre, Cynthia, Keszei, Marton, Garrido-Mesa, Natividad, Kis-Toth, Katalin, Castro, Wilson, Agyemang, Amma F., Veerapen, Natacha, Besra, Gurdyal S., Carroll, Michael C., Tsokos, George C., Wang, Ninghai, Leadbetter, Elizabeth A., Terhorst, Cox
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2012
Assuntos:
Immunobiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3390951/
https://ncbi.nlm.nih.gov/pubmed/22613797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-11-395913
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