Cognate interaction with iNKT cells expands IL-10–producing B regulatory cells

Successful induction of B-cell activation and memory depends on help from CD4(+) T cells. Invariant natural killer T (iNKT) cells (glycolipid-specific, CD1d-restricted innate lymphocytes) provide both cognate (direct) and noncognate (indirect) helper signals to enhance B-cell responses. Both forms o...

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Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Vomhof-DeKrey, Emilie E., Yates, Jennifer, Hägglöf, Thomas, Lanthier, Paula, Amiel, Eyal, Veerapen, Natacha, Besra, Gurdyal S., Karlsson, Mikael C. I., Leadbetter, Elizabeth A.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2015
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4603516/
https://ncbi.nlm.nih.gov/pubmed/26392556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1504790112
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