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Influence of CYP2B6 genetic variants on plasma and urine concentrations of bupropion and metabolites at steady state
BACKGROUND: Bupropion, an antidepressant and smoking cessation medication, is metabolized to hydroxybupropion (HB), an active metabolite, primarily by CYP2B6. OBJECTIVES: To compare plasma concentrations of bupropion and metabolites at steady state in healthy volunteers with and without CYP2B6 genet...
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| Hlavní autoři: | , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2013
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3763712/ https://ncbi.nlm.nih.gov/pubmed/23344581 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FPC.0b013e32835d9ab0 |
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