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Estimation of Nicotine Dose after Low Level Exposure Using Plasma and Urine Nicotine Metabolites

BACKGROUND: We sought to determine the optimal plasma and urine nicotine metabolites, alone or in combination, to estimate the systemic dose of nicotine after low level exposure. METHODS: We dosed 36 nonsmokers with 100, 200 or 400 μg deuterium-labeled nicotine (doses similar to exposure to secondha...

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Detalhes bibliográficos
Main Authors: Benowitz, Neal L., Dains, Katherine M., Dempsey, Delia, Yu, Lisa, Jacob, Peyton
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2867075/
https://ncbi.nlm.nih.gov/pubmed/20447913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-09-1303
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