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Berberine Reduces the Metastasis of Chondrosarcoma by Modulating the αvβ3 Integrin and the PKCδ, c-Src, and AP-1 Signaling Pathways

Chondrosarcoma is a primary malignant bone cancer, with a potent capacity to invade locally and cause distant metastasis, especially to the lungs. Patients diagnosed with chondrosarcoma have poor prognosis. Berberine, an active component of the Ranunculaceae and Papaveraceae families of plant, has b...

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Autores principales: Wu, Chi-Ming, Li, Te-Mao, Tan, Tzu-Wei, Fong, Yi-Chin, Tang, Chih-Hsin
Formato: Artigo
Lenguaje:Inglês
Publicado: Hindawi Publishing Corporation 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3763569/
https://ncbi.nlm.nih.gov/pubmed/24027594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/423164
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