Paeonol Suppresses Chondrosarcoma Metastasis through Up-Regulation of miR-141 by Modulating PKCδ and c-Src Signaling Pathway

Chondrosarcoma, a primary malignant bone cancer, has potential for local invasion and distant metastasis, especially to the lungs. Patients diagnosed with it show poor prognosis. Paeonol (2'-hydroxy-4'-methoxyacetophenone), the main active compound of traditional Chinese remedy Paeonia lac...

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Détails bibliographiques
Auteurs principaux: Horng, Chi-Ting, Shieh, Po-Chuen, Tan, Tzu-Wei, Yang, Wei-Hung, Tang, Chih-Hsin
Format: Artigo
Langue:Inglês
Publié: MDPI 2014
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4139812/
https://ncbi.nlm.nih.gov/pubmed/24992595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms150711760
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