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Cellular-Level Versus Receptor-Level Response Threshold Hierarchies in T-Cell Activation
Peptide-MHC (pMHC) ligand engagement by T-cell receptors (TCRs) elicits a variety of cellular responses, some of which require substantially more TCR-mediated stimulation than others. This threshold hierarchy could reside at the receptor level, where different response pathways branch off at differe...
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| Main Authors: | , , , , , , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Frontiers Media S.A.
2013
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3763380/ https://ncbi.nlm.nih.gov/pubmed/24046768 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2013.00250 |
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