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Architecture and DNA Recognition Elements of the Fanconi Anemia FANCM-FAAP24 Complex
Fanconi anemia (FA) is a disorder associated with a failure in DNA repair. FANCM (defective in FA complementation group M) and its partner FAAP24 target other FA proteins to sites of DNA damage. FANCM-FAAP24 is related to XPF/MUS81 endonucleases but lacks endonucleolytic activity. We report a struct...
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| Asıl Yazarlar: | , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Cell Press
2013
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3763369/ https://ncbi.nlm.nih.gov/pubmed/23932590 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2013.07.006 |
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