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The Fanconi anemia associated protein FAAP24 uses two substrate specific binding surfaces for DNA recognition

To maintain the integrity of the genome, multiple DNA repair systems exist to repair damaged DNA. Recognition of altered DNA, including bulky adducts, pyrimidine dimers and interstrand crosslinks (ICL), partially depends on proteins containing helix-hairpin-helix (HhH) domains. To understand how ICL...

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Detalhes bibliográficos
Main Authors: Wienk, Hans, Slootweg, Jack C., Speerstra, Sietske, Kaptein, Robert, Boelens, Rolf, Folkers, Gert E.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3711432/
https://ncbi.nlm.nih.gov/pubmed/23661679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt354
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