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The Fanconi anemia associated protein FAAP24 uses two substrate specific binding surfaces for DNA recognition

To maintain the integrity of the genome, multiple DNA repair systems exist to repair damaged DNA. Recognition of altered DNA, including bulky adducts, pyrimidine dimers and interstrand crosslinks (ICL), partially depends on proteins containing helix-hairpin-helix (HhH) domains. To understand how ICL...

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Hlavní autoři: Wienk, Hans, Slootweg, Jack C., Speerstra, Sietske, Kaptein, Robert, Boelens, Rolf, Folkers, Gert E.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3711432/
https://ncbi.nlm.nih.gov/pubmed/23661679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt354
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