REDOX REGULATION OF SIRT1 IN INFLAMMATION AND CELLULAR SENESCENCE

Sirtuin1 (SIRT1) regulates inflammation, aging (lifespan and healthspan), calorie restriction/energetics, mitochondrial biogenesis, stress resistance, cellular senescence, endothelial functions, apoptosis/autophagy, and circadian rhythms through deacetylation of transcription factors and histones. S...

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Bibliographic Details
Main Authors: Hwang, Jae-woong, Yao, Hongwei, Caito, Samuel, Sundar, Isaac K., Rahman, Irfan
Format: Artigo
Language:Inglês
Published: 2013
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3762912/
https://ncbi.nlm.nih.gov/pubmed/23542362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2013.03.015
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