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The Tumor-Selective Cytotoxic Agent β-Lapachone is a Potent Inhibitor of IDO1
β-lapachone is a naturally occurring 1,2-naphthoquinone-based compound that has been advanced into clinical trials based on its tumor-selective cytotoxic properties. Previously, we focused on the related 1,4-naphthoquinone pharmacophore as a basic core structure for developing a series of potent ind...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Libertas Academica
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3762611/ https://ncbi.nlm.nih.gov/pubmed/24023520 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4137/IJTR.S12094 |
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