تحميل...
Constitutive Production of NF-κB2 p52 Is Not Tumorigenic but Predisposes Mice to Inflammatory Autoimmune Disease by Repressing Bim Expression
Normal development of the immune system requires regulated processing of NF-κB2 p100 to p52, which activates NF-κB2 signaling. Constitutive production of p52 has been suggested as a major mechanism underlying lymphomagenesis induced by NF-κB2 mutations, which occur recurrently in a variety of human...
محفوظ في:
| المؤلفون الرئيسيون: | , , , , |
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| التنسيق: | Artigo |
| اللغة: | Inglês |
| منشور في: |
American Society for Biochemistry and Molecular Biology
2008
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| الوصول للمادة أونلاين: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3762532/ https://ncbi.nlm.nih.gov/pubmed/18281283 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M800806200 |
| الوسوم: |
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