ロード中...

Analogs of Iso-Azepinomycin as Potential Transition-State Analog Inhibitors of Guanase: Synthesis, Biochemical Screening, and Structure-Activity Correlations of Various Selectively Substituted Imidazo[4,5-e][1,4]diazepines

Guanase is an important enzyme of the purine salvage pathway of nucleic acid metabolism and its inhibition has beneficial implications in viral, bacterial, and cancer therapy. The work described herein is based on a hypothesis that azepinomycin, a heterocyclic natural product and a purported transit...

詳細記述

保存先:
書誌詳細
主要な著者: Tantravedi, Saritha, Chakraborty, Saibal, Shah, Niti H., Fishbein, James C., Hosmane, Ramachandra S.
フォーマット: Artigo
言語:Inglês
出版事項: 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3761942/
https://ncbi.nlm.nih.gov/pubmed/23891230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2013.06.069
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!