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A Novel Transition State Analogue Inhibitor of Guanase Based on Azepinomycin Ring Structure: Synthesis and Biochemical Assessment of Enzyme Inhibition
Synthesis and biochemical inhibition studies of a novel transition state analogue inhibitor of guanase bearing the ring structure of azepinomycin have been reported. The compound was synthesized in five steps from a known compound and biochemically screened against the rabbit liver guanase. The comp...
Gorde:
| Egile Nagusiak: | , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2011
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3035156/ https://ncbi.nlm.nih.gov/pubmed/21183343 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2010.11.109 |
| Etiketak: |
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