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A Novel, Broad Spectrum Anti-Cancer Compound Containing the Imidazo[4,5-e][1,3]diazepine Ring System

Synthesis and broad-spectrum anticancer activity of a novel heterocyclic compound 1 containing the title imidazo[4,5-e][1,3]diazepine ring system have been reported. The compound shows potent in vitro antitumor activity with low micromolar IC(50)’s against prostate, lung, breast, and ovarian cancer...

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Detalhes bibliográficos
Main Authors: Xie, Min, Ujjinamatada, Ravi K., Sadowska, Mariola, Lapidus, Rena G., Edelman, Martin J., Hosmane, Ramachandra S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2905507/
https://ncbi.nlm.nih.gov/pubmed/20594843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2010.06.061
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