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Biophysical Basis of the Promiscuous Binding of Bcl2 Apoptotic Repressor to BH3 Ligands
Bcl2 apoptotic repressor carries out its function by virtue of its ability to bind to BH3 domains of various pro-apoptotic regulators in a highly promiscuous manner. Herein, we investigate the biophysical basis of such promiscuity of Bcl2 toward its cognate BH3 ligands. Our data show that while the...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3761409/ https://ncbi.nlm.nih.gov/pubmed/23996493 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jmr.2295 |
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