Heat-Induced Fibrillation of BclXL Apoptotic Repressor

The BclXL apoptotic repressor bears the propensity to associate into megadalton oligomers in solution, particularly under acidic pH. Herein, using various biophysical methods, we analyze the effect of temperature on the oligomerization of BclXL. Our data show that BclXL undergoes irreversible aggreg...

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Detalhes bibliográficos
Main Authors: Bhat, Vikas, Olenick, Max B., Schuchardt, Brett J., Mikles, David C., Deegan, Brian J., McDonald, Caleb B., Seldeen, Kenneth L., Kurouski, Dmitry, Faridi, Mohd Hafeez, Shareef, Mohammed M., Gupta, Vineet, Lednev, Igor K., Farooq, Amjad
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3706518/
https://ncbi.nlm.nih.gov/pubmed/23714425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpc.2013.04.002
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