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Heat-Induced Fibrillation of BclXL Apoptotic Repressor

The BclXL apoptotic repressor bears the propensity to associate into megadalton oligomers in solution, particularly under acidic pH. Herein, using various biophysical methods, we analyze the effect of temperature on the oligomerization of BclXL. Our data show that BclXL undergoes irreversible aggreg...

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Bibliografische gegevens
Hoofdauteurs: Bhat, Vikas, Olenick, Max B., Schuchardt, Brett J., Mikles, David C., Deegan, Brian J., McDonald, Caleb B., Seldeen, Kenneth L., Kurouski, Dmitry, Faridi, Mohd Hafeez, Shareef, Mohammed M., Gupta, Vineet, Lednev, Igor K., Farooq, Amjad
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2013
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3706518/
https://ncbi.nlm.nih.gov/pubmed/23714425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpc.2013.04.002
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