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Characterization of a cellular denitrase activity that reverses nitration of cyclooxygenase

Protein 3-nitrotyrosine (3-NT) formation is frequently regarded as a simple biomarker of disease, an irreversible posttranslational modification that can disrupt protein structure and function. Nevertheless, evidence that protein 3-NT modifications may be site selective and reversible, thus allowing...

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Autores principales: Deeb, Ruba S., Nuriel, Tal, Cheung, Cynthia, Summers, Barbara, Lamon, Brian D., Gross, Steven S., Hajjar, David P.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Physiological Society 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3761327/
https://ncbi.nlm.nih.gov/pubmed/23792683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00876.2012
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