Inducible Nitric Oxide Synthase Mediates Prostaglandin H(2) Synthase Nitration and Suppresses Eicosanoid Production

Nitric oxide (NO) modulates the biological levels of arachidonate-derived cell signaling molecules by either enhancing or suppressing the activity of prostaglandin H(2) isoforms (PGHS-1 and PGHS-2). Whether NO activates or suppresses PGHS activity is determined by alternative protein modifications m...

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Main Authors: Deeb, Ruba S., Shen, Hao, Gamss, Caryn, Gavrilova, Tatyana, Summers, Barbara D., Kraemer, Rosemary, Hao, Gang, Gross, Steven S., Lainé, Muriel, Maeda, Nobuyo, Hajjar, David P., Upmacis, Rita K.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Investigative Pathology 2006
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1592660/
https://ncbi.nlm.nih.gov/pubmed/16400036
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