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Physical evidence for substrate binding in preventing cyclooxygenase inactivation under nitrative stress

Prostaglandin biosynthesis is catalyzed by two spatially and functionally distinct active sites in cyclooxygenase (COX) enzymes. Despite the crucial role of COXs in biology, molecular details regarding the function and regulation of these enzymes are incompletely defined. Reactive nitrogen species (...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Deeb, Ruba S., Cheung, Cynthia, Nuriel, Tal, Lamon, Brian D., Upmacis, Rita K., Gross, Steven S., Hajjar, David P.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2010
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2866047/
https://ncbi.nlm.nih.gov/pubmed/20196542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja910578y
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