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Protein 3-Nitrotyrosine in Complex Biological Samples: Quantification by High-Pressure Liquid Chromatography/Electrochemical Detection and Emergence of Proteomic Approaches for Unbiased Identification of Modification Sites

Nitration of tyrosine residues by nitric oxide (NO)-derived species results in the accumulation of 3-nitrotyrosine in proteins, a hallmark of nitrosative stress in cells and tissues. Tyrosine nitration is recognized as one of the multiple signaling modalities used by NO-derived species for the regul...

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Detalhes bibliográficos
Main Authors: Nuriel, Tal, Deeb, Ruba S., Hajjar, David P., Gross, Steven S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2483310/
https://ncbi.nlm.nih.gov/pubmed/18554526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0076-6879(08)01201-9
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