CXCL12 induces hepatic stellate cell contraction through a calcium-independent pathway

Liver fibrosis, with subsequent development of cirrhosis and ultimately portal hypertension, results in the death of patients with end-stage liver disease if liver transplantation is not performed. Hepatic stellate cells (HSCs), central mediators of liver fibrosis, resemble tissue pericytes and regu...

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Main Authors: Saiman, Yedidya, Agarwal, Ritu, Hickman, DaShawn A., Fausther, Michel, El-Shamy, Ahmed, Dranoff, Jonathan A., Friedman, Scott L., Bansal, Meena B.
Formato: Artigo
Idioma:Inglês
Publicado: American Physiological Society 2013
Assuntos:
Liver and Biliary Tract
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3761245/
https://ncbi.nlm.nih.gov/pubmed/23812037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00185.2012
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