X4 Human Immunodeficiency Virus Type 1 gp120 Promotes Human Hepatic Stellate Cell Activation and Collagen I Expression through Interactions with CXCR4

BACKGROUND & AIMS: Patients coinfected with HIV-1 and HCV develop more rapid liver fibrosis than patients monoinfected with HCV. HIV RNA levels correlate with fibrosis progression implicating HIV directly in the fibrotic process. While activated hepatic stellate cells (HSCs) express the 2 major...

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Detalhes bibliográficos
Main Authors: Hong, Feng, Saiman, Yedidya, Si, Chuanping, Mosoian, Arevik, Bansal, Meena B.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3313947/
https://ncbi.nlm.nih.gov/pubmed/22479424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0033659
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