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Distinct signaling mechanisms regulate migration in unconfined versus confined spaces
Using a microchannel assay, we demonstrate that cells adopt distinct signaling strategies to modulate cell migration in different physical microenvironments. We studied α4β1 integrin–mediated signaling, which regulates cell migration pertinent to embryonic development, leukocyte trafficking, and mel...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Rockefeller University Press
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3760608/ https://ncbi.nlm.nih.gov/pubmed/23979717 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201302132 |
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