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Distinct signaling mechanisms regulate migration in unconfined versus confined spaces

Using a microchannel assay, we demonstrate that cells adopt distinct signaling strategies to modulate cell migration in different physical microenvironments. We studied α4β1 integrin–mediated signaling, which regulates cell migration pertinent to embryonic development, leukocyte trafficking, and mel...

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Podrobná bibliografie
Hlavní autoři: Hung, Wei-Chien, Chen, Shih-Hsun, Paul, Colin D., Stroka, Kimberly M., Lo, Ying-Chun, Yang, Joy T., Konstantopoulos, Konstantinos
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3760608/
https://ncbi.nlm.nih.gov/pubmed/23979717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201302132
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