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Physical confinement alters tumor cell adhesion and migration phenotypes
Cell migration on planar surfaces is driven by cycles of actin protrusion, integrin-mediated adhesion, and myosin-mediated contraction; however, this mechanism may not accurately describe movement in 3-dimensional (3D) space. By subjecting cells to restrictive 3D environments, we demonstrate that ph...
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| Главные авторы: | , , , , , , , |
|---|---|
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Federation of American Societies for Experimental Biology
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3448771/ https://ncbi.nlm.nih.gov/pubmed/22707566 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.12-211441 |
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