Physical confinement alters tumor cell adhesion and migration phenotypes

Cell migration on planar surfaces is driven by cycles of actin protrusion, integrin-mediated adhesion, and myosin-mediated contraction; however, this mechanism may not accurately describe movement in 3-dimensional (3D) space. By subjecting cells to restrictive 3D environments, we demonstrate that ph...

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Bibliografiska uppgifter
Huvudupphovsmän: Balzer, Eric M., Tong, Ziqiu, Paul, Colin D., Hung, Wei-Chien, Stroka, Kimberly M., Boggs, Amanda E., Martin, Stuart S., Konstantopoulos, Konstantinos
Materialtyp: Artigo
Språk:Inglês
Publicerad: Federation of American Societies for Experimental Biology 2012
Ämnen:
Research Communications
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3448771/
https://ncbi.nlm.nih.gov/pubmed/22707566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.12-211441
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