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The FHA and BRCT domains recognize ADP-ribosylation during DNA damage response

Poly-ADP-ribosylation is a unique post-translational modification participating in many biological processes, such as DNA damage response. Here, we demonstrate that a set of Forkhead-associated (FHA) and BRCA1 C-terminal (BRCT) domains recognizes poly(ADP-ribose) (PAR) both in vitro and in vivo. Amo...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Li, Mo, Lu, Lin-Yu, Yang, Chao-Yie, Wang, Shaomeng, Yu, Xiaochun
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3759693/
https://ncbi.nlm.nih.gov/pubmed/23964092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.226357.113
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