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C-Fos Regulation by the MAPK and PKC Pathways in Intervertebral Disc Cells

BACKGROUND: The gene encoding c-fos is an important factor in the pathogenesis of joint disease in patients with osteoarthritis. However, it is unknown whether the signal mechanism of c-fos acts in intervertebral disc (IVD) cells. We investigated whether c-fos is activated in relation to mitogen-act...

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Autors principals: Yokoyama, Katsuya, Hiyama, Akihiko, Arai, Fumiyuki, Nukaga, Tadashi, Sakai, Daisuke, Mochida, Joji
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3759433/
https://ncbi.nlm.nih.gov/pubmed/24023832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0073210
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