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Enhancement of Intervertebral Disc Cell Senescence by WNT/β-Catenin Signaling–Induced Matrix Metalloproteinase Expression
OBJECTIVE: To determine whether intervertebral disc (IVD) cells express β-catenin and to assess the role of the WNT/β-catenin signaling pathway in cellular senescence and aggrecan synthesis. METHODS: The expression of β-catenin messenger RNA (mRNA) and protein in rat IVD cells was assessed by using...
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| Main Authors: | , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2010
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3622204/ https://ncbi.nlm.nih.gov/pubmed/20533544 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.27599 |
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